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Director: Meenakshi Bidwa Bhattacharjee, M.D., B.S.
Email: mbb@bcm.tmc.edu
Phone: 832-824-2250 |
Lab Supervisor: Barbara Antalffy, B.S.
Email: antalffy@bcm.tmc.edu
Phone: 832-824-3957 |
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The objective of the Neuropathology
Laboratory is to provide a facility for the members of the MRDDRC that
is equipped for and experienced in the preparation and interpretation
of histology, histochemistry, immunocytochemistry, in situ
hybridization preparations and ultrastructural studies of the nervous
system.
The Baylor MRDDRC consists of researchers working within various areas
of expertise, in which human and animal tissues are investigated in
order to characterize molecular, chemical and morphologic markers. The
morphologic studies include the demonstration of gene products within
cells, identification of specific cell types, histochemical identification
of enzyme activity, ultrastructural characterization of cell organelles,
confirmation of the presence of pathognomonic lesions in human and animal
study subjects, and the identification of the presence or absence of
structural integrity of the nervous system in transgenic and mutant
animal models of human disease. The neuropathology core provides support
for these necessary studies. Careful neuropathologic and immuno- localization
analyses MRDD and the function of neuronal and developmental genes.
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